Phenylpiracetam

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WARNING: This product is not for human or veterinary use.

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Product Description

Buy Phenylpiracetam

Venogen offers certified Phenylpiracetam for sale online in 10mg reference standards, for research purposes only.

What is Phenylpiracetam?

Phenylpiracetam (also known as Phenotropil and Carphedon) is a potent nootropic drug belonging to the racetam family of chemical compounds, which includes the well known drug piracetam. Piracetam is in turn a derivative of the nootropic supplement GABA (gamma-amino butyric acid). Nootropic supplements such as phenylpiracetam, piracetam and others in the racetam family are the subject of long-standing scientific interest for their potential to improve cognitive function and mental activity [a].

Phenylpiracetam has been banned by the World Anti-Doping Agency, as athletes increasingly seek out performance enhancing drugs to improve not only their physical performance, but also their reaction speed, concentration, mental drive and other aspects of their cognitive performance [b].

It is sold online through Venogen as Phenylpiracetam powder (not as Phenylpiracetam capsules).

Its molecular weight is 218.25, and its molecular formula is C12H14N2O2 [c].

Modes of action

Phenylpiracetam works by binding to acetylcholine receptors in the brain [d]. The addition of the bulk phenyl grouping (a six sided cyclic ring linked via a single carbon atom) on the pyrrolidone lactam ring makes the compound slightly lipid soluble, improving its ability to cross the blood brain barrier [e].

Animal Studies

In a 2007 study, Russian scientists compared the effects of Phenylpiracetam with Piracetam in rats with induced cerebral ischemia, and found that, after restoration of blood flow, the rats maintained better cognitive functions after treatment with Phenylpiracetam than with Piracetam [f].

A 2011 study reported that, after administration of Phenylpiracetam, it was possible to treat rats with Scopolamine without observing the memory loss that would typically occur. It also found that administration of Phenylpiracetam significantly increased the density of dopamine receptors [g].

In the same year, another study in Wistar rats reported better maintenance of cognitive function after treatment with Phenylpiracetam, despite experimentally induced immune stress [h].

This was followed up in 2013 by a further study in Wistar rats, which also found that Phenylpiracetam improved the animals’ ability to cope with a wider range of stressful situations [i].

A 2017 study in obese rats found that Phenotropil was useful in preventing fat accumulation [j].

A 2020 study in male rats reported that Phenylpiracetam had benefits as a neuroprotective agent, as well as anti-inflammatory benefits [k].

Human Studies

A 2010 paper reviewed human clinical trials, and reported that phenylpiracetam appeared to have a positive effect on various cognitive disabilities (such as those caused by traumatic brain injury), and also that it improved concentration, focus and energy levels in healthy individuals (without diagnosed health conditions) [l].

Why buy Phenibut online through Venogen?

Our Phenylpiracetam (and all our other products offered) has been independently audited by batch (lab tested) and produced within a GMP facility. Venogen is a solid choice if you are looking to buy Phenylpiracetam online (GMP produced). We are a long-established vendor of analytical research chemicals for laboratory research use, and are proud of our great customer service. Our products are of the highest quality, and we are proud of our fast shipping and excellent customer service. We have quality Phenylpiracetam powder for sale with a high product purity.

Legal Disclaimer

We recommend purchasing Phenylpiracetam online for laboratory research purposes only, not for human consumption. Although researchers demonstrated that human use of Phenibut HCl powder or Phenibut Hcl capsules may have beneficial effects, further clinical trials are required for this substance to be FDA approved. We offer Phenylpiracetam powder for sale online as an experimental compound that is not intended for human consumption or veterinary use.

Venogen does not sell Phenylpiracetam for customers to use for recreational purposes, including cognitive enhancement.

If you purchase Phenylpiracetam, in order to maximise its shelf life, we recommend that you store it in a cool dry place away from direct sunlight.

References

[a] Gouliaev AH, Senning A. Piracetam and other structurally related nootropics. Brain Research Reviews. 1994;19(2):180-222. doi:10.1016/0165-0173(94)90011-6

[b] Smith AC, Stavros C, Westberg K. Cognitive enhancing drugs in sport: Current and future concerns. Substance Use & Misuse. 2020;55(12):2064-2075. doi:10.1080/10826084.2020.1775652

[c] Fonturacetam. National Center for Biotechnology Information. PubChem Compound Database. https://pubchem.ncbi.nlm.nih.gov/compound/132441. Accessed October 15, 2022.

[d] Zvejniece L, Svalbe B, Veinberg G, et al. Investigation into stereoselective pharmacological activity of Phenotropil. Basic & Clinical Pharmacology & Toxicology. 2011;109(5):407-412. doi:10.1111/j.1742-7843.2011.00742.x

[e] Han J, Escorihuela J, Fustero S, Landa A, Soloshonok VA, Sorochinsky A. Asymmetric Michael addition in synthesis of β-substituted GABA derivatives. Molecules. 2022;27(12):3797. doi:10.3390/molecules27123797

[f] Tiurenkov IN, Bagmetov MN, Epishina VV. [Comparative evaluation of the neuroprotective activity of phenotropil and piracetam in laboratory animals with experimental cerebral ischemia]. Eksperimental’naia i Klinicheskaia Farmakologiia. January 2007:6-10.

[g] Firstova YY, Abaimov DA, Kapitsa IG, Voronina TA, Kovalev GI. The effects of scopolamine and the nootropic drug Phenotropil on rat brain neurotransmitter receptors during testing of the conditioned passive avoidance task. Neurochemical Journal. 2011;5(2):115-125. doi:10.1134/s1819712411020048

[h] Samotrueva MA, Tyurenkov IN, Teplyi DL, Serezhnikova TK, Khlebtsova EB. Psychoimmunomodulatory effect of Phenotropil in animals with immune stress. Bulletin of Experimental Biology and Medicine. 2011;151(1):51-54. doi:10.1007/s10517-011-1257-4

[i] Samotrueva MA, Tyurenkov IN, Teplyi DL, et al. Phenotropil succinate as a substance correcting neuroimmune impairments in conditions of informational-physical stress. Neuroscience and Behavioral Physiology. 2013;43(1):135-138. doi:10.1007/s11055-012-9703-y

[j] Zvejniece L, Svalbe B, Vavers E, et al. S -phenylpiracetam, a selective DAT inhibitor, reduces body weight gain without influencing locomotor activity. Pharmacology Biochemistry and Behavior. 2017;160:21-29. doi:10.1016/j.pbb.2017.07.009

[k] Zvejniece L, Zvejniece B, Videja M, et al. Neuroprotective and anti-inflammatory activity of DAT inhibitor R-phenylpiracetam in experimental models of inflammation in male mice. Inflammopharmacology. 2020;28(5):1283-1292. doi:10.1007/s10787-020-00705-7

[l] Malykh AG, Sadaie MR. Piracetam and piracetam-like drugs. Drugs. 2010;70(3):287-312. doi:10.2165/11319230-000000000-00000

Technical Information and Resources

 

Formula Weight: 218.3
Molecular formula: C12H14N2O2
λmax: N/A
InChIKey: LYONXVJRBWWGQO-UHFFFAOYSA-N
Pubchem Compund ID: 132441

Product Information

CAS
77472-70-9
UNII
99QW5JU66Y
EINECS
N/A
Purity
99%
Stability
≥ 2 years