MK-2866 (Ostarine,Enobosarm)

USD $60.00 Bulk Pricing

WARNING: This product is not for human or veterinary use.

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Product Description

Buy MK2866 Ostarine

 

Venogen offers certified GMP MK-2866 Ostarine for sale in 10mg reference standards.

What is MK-2866 Ostarine?

 

MK-2866 is a Selective Androgen Receptor Modulator (SARM). Its molecular weight is 389.3 grams per mole, and its chemical formula is C19H14F3N3O3 [a]. It is trademarked under the name Ostarine, by Oncternal Therapeutics Inc. Selective Androgen Receptor Modulators are the subject of ongoing clinical trials investigating their potential to rebuild muscle mass in patients suffering from muscle wasting [b]. The FDA has warned against human consumption of SARMs to achieve muscle gain and fat loss, due to the risk of severe adverse effects on liver and heart health [c]. Scientists are interested in the use of Ostarine MK 2866 to increase lean body mass in cancer patients with cachexia (a syndrome involving muscle loss) as well as to combat insulin resistance in those patients [d].

Modes of action

 

Ostarine MK-2866 binds to androgen receptors on a selective basis, preferentially acting on muscle tissue rather than the liver or prostate [e]. Such stimulation is well known to lead to increases in lean muscle mass.

The half life of MK-2866 Ostarine has been estimated as 24 hours [d].

Animal Research

 

A 2018 in vivo study found that Ostarine MK2866 improved bone density in ovariectomized rats (simulating osteoporosis after menopause) [f].

In 2019, another in vivo study found that MK-2866 had a positive effect on bone healing and bone density in orchiectomized rats [g].

A 2020 in vitro study in rat tissue found benefits on muscle cell proliferation and protein synthesis [e].

Human Research

 

A 2011 study in elderly test subjects (healthy elderly men and postmenopausal women) found that Ostarine MK2866 increased lean muscle mass and significantly improved physical function [h].

Why buy Ostarine online through Venogen?

 

All Venogen chemicals have been independently audited by batch and produced within a GMP facility. Venogen is a solid choice if you are looking for lab-tested MK-2866 online (GMP produced). We are a long-established vendor of analytical research chemicals for laboratory research use. Our products sold are of the highest quality, and we are proud of our fast shipping and good customer service. We have quality MK 2866 for sale with a high product purity.

Disclaimer

 

The Ostarine MK-2866 for sale on this website is intended for laboratory research purposes only. Although researchers demonstrated that human use of this drug may have beneficial effects on the human body in clinical studies, the studies are inconclusive within a proper medical setting and conducted for research purposes only. Our company does not recommend to buy SARMs for use buy humans seeking to achieve muscle growth or fat burning. Our store offers Ostarine for sale online for research use only. This is an experimental compound that is not intended for human consumption or veterinarian use.

Other Notes

 

Please be sure to store Ostarine MK 2866 in a cool dry place, as open air exposure may lead to degradation of the product.

References

 

[a] Enobosarm. National Center for Biotechnology Information. PubChem Compound Database. https://pubchem.ncbi.nlm.nih.gov/compound/11326715. Accessed August 30, 2022.

[b] Fonseca GW, Dworatzek E, Ebner N, Von Haehling S. Selective androgen receptor modulators (sarms) as pharmacological treatment for muscle wasting in ongoing clinical trials. Expert Opinion on Investigational Drugs. 2020;29(8):881-891. doi:10.1080/13543784.2020.1777275

[c] Commissioner of the. FDA in brief: FDA warns against using Sarms in body-building products. U.S. Food and Drug Administration. https://www.fda.gov/news-events/fda-brief/fda-brief-fda-warns-against-using-sarms-body-building-products. Accessed August 30, 2022.

[d] Zilbermint MF, Dobs AS. Nonsteroidal selective androgen receptor modulator ostarine™ in cancer cachexia. Future Oncology. 2009;5(8):1211-1220. doi:10.2217/fon.09.106

[e] Walton CM, Saito E, Jacobsen S, Thomson DM, Bikman BT. Selective androgen receptor modulation with MK‐2866 favorably alters muscle mitochondrial bioenergetics. The FASEB Journal. 2020;34(S1):1-1. doi:10.1096/fasebj.2020.34.s1.03725

[f] Hoffmann DB, Komrakova M, Pflug S, et al. Evaluation of ostarine as a selective androgen receptor modulator in a rat model of postmenopausal osteoporosis. Journal of Bone and Mineral Metabolism. 2018;37(2):243-255. doi:10.1007/s00774-018-0929-9

[g] Komrakova M, Anders C, Böker KO, et al. The effect of selective androgen and/or estrogen receptor modulators on bone healing in a rat model of aged male osteoporosis. Healthy Aging – Bone and Joint. 2019. doi:10.1055/s-0039-1679998

[h] Dalton JT, Barnette KG, Bohl CE, et al. The selective androgen receptor modulator GTX‐024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: Results of a double‐blind, placebo‐controlled phase II trial. Journal of Cachexia, Sarcopenia and Muscle. 2011;2(3):153-161. doi:10.1007/s13539-011-0034-6

Technical Information and Resources

 

Formula Weight: 389.3
Molecular formula: C19H14F3N3O3
λmax: N/A
InChIKey: JNGVJMBLXIUVRD-SFHVURJKSA-N
Pubchem Compund ID: 11326715

Product Information

CAS
841205-47-8
UNII
O3571H3R8N
EINECS
N/A
Purity
99%
Stability
≥ 2 years